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Writer panagene     (Date : 2008-04-27 22:21:00)
Subject How can I incorporate a specially modified monomer into PNA sequence?
Content

Our oligomerization chemistry using Bts monomers is compatible with Fmoc chemistry. After deprotection of Bts during PNA synthesis, a specially modified monomer protected with Fmoc can be coupled by conventional method. Otherwise, Bts monomer can be coupled after Fmoc deprotecion of PNA or peptide. You can freely incoporate a modified monomer into PNA where you want.



 

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