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(ÁÖ)ÆijªÁøÀº microRNA (miRNA) ¿¬±¸¸¦ À§ÇÑ Á¦Ç°±ºÀ» Áö¼ÓÀûÀ¸·Î Ãâ½ÃÇÏ°í ÀÖ½À´Ï´Ù. PNAs miRNA inhibitor Àç°í´Â ²ÙÁØÈ÷ È®º¸ÇÏ°í ÀÖÀ¸¸ç, 2009³â 7¿ù ÇöÀç ÷ºÎÆÄÀÏ¿¡¼¿Í °°ÀÌ ¾à 130¿© Á¾À» º¸À¯ÇÏ°í ÀÖ½À´Ï´Ù.
¶ÇÇÑ, ÃÖ±Ù¿¡´Â FAM-labeled miRNA inhibitorÀÇ °¡°ÝÀ» ´ëÆøÇÒÀÎÇÏ¿© Á¦°øÇϱ⠽ÃÀÛÇßÀ¸¸ç, °¡°ÝÀº ¾Æ·¡¿Í °°½À´Ï´Ù.
Á¦Ç° |
Amount (nmole) |
°¡°Ý (¿ø) |
PNAs¢â miRNA inhibitor |
5 |
95,000 |
25 |
195,000 |
FAM-PNAs¢â miRNA inhibitor |
5 |
190,000 |
FAM-Negative control |
5 |
95,000 |
25 |
195,000 |
(ÁÖ)ÆijªÁøÀº Ç×»ó ¿¬±¸ÀÚµéÀÇ ¿¬±¸¿¡ ´õ ÁÁÀº Á¦Ç°À» Á¦°øÇص帮°íÀÚ ³ë·ÂÇÏ°í ÀÖ½À´Ï´Ù. ±Ã±ÝÇϽŠÁ¡À̳ª ÇÏ½Ç ¸»¾¸ÀÌ ÀÖÀ¸½Ã¸é ¾ðÁ¦µç ¿¬¶ôÁÖ½Ã¸é ¼º½É¼ºÀDz¯ ´äº¯µå¸®°Ú½À´Ï´Ù.
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