Welcome > Support > Âü°íÀÚ·á  
 
 
E
 
±Ûº¸±â
¼º¸í ÆijªÁø     (Date : 2010-12-21 15:52:50)
Á¦¸ñ [³í¹®] [PNA Chip vs DNA Chip ÀÓ»ó½ÇÇè ³í¹®]
³»¿ë

ÇöÀç »ç¾÷ ÁßÀÎ PANArray¢â HPV Genotyping Chip°ú DNA ChipÀÇ ºñ±³ ³í¹®ÀÌ ¾Æ·¡¿Í °°ÀÌ  BioChip journal¿¡ °ÔÀçµÇ¾ú½À´Ï´Ù.


Á¦¸ñ :
Comparison of the performance of the PANArray¢â HPV test and DNA chip test for genotyping of human papillomavirus in cervical swabs

ÀúÀÚ :
Hye Jong Song, Jeong Won Lee, Byoung Gie Kim, Sang Yong Song, Duk Soo Bae & Dae Shick Kim

Ãâó :
Received: 5 March 2010 / Accepted: 20 May 2010 / Published online: 20 September 2010
􀋄 The Korean BioChip Society and Springer 2010

¹ßÇ࿬µµ : 2010

ÁÖÁ¦Å°¿öµå : PNA, PNA microarray, Human papillomavirus(HPV), HPV genotyping


ÃÊ·Ï(¿µ¹®) :
The aim of this study was to evaluate the recently developed PANArrayTM Human papilloma virus (HPV) kit for detection and genotyping of 19 high-risk and 13 low-risk HPV types, and compare it with the commercially available DNA chip kit genotyping of 24 HPVs. We collected cervical swabs from 741 patients with various stages of invasive cervical
carcinoma being treated at the Samsung Medical Center. The overall HPV positivity rate was 73% using PANArrayTM HPV and 72.1% with the DNA chip, and no statistically significant differences were found with respect to the cytology grade. Comparing the results of the two chips, concordant results were found in 637/741 samples (85.9%), compatible in 69/741(9.3%) and discordant in 35/741 (4.7%). Type-specific sequencing analysis of all samples revealed a 99.7% confirmation of PANArrayTM HPV genotyping results, compared to 91.0% of DNA chip. The PANArrayTM HPV test thus proved to be highly sensitive and accurate even when multiple HPV infections were present.

* ÀÚ¼¼ÇÑ »çÇ×Àº ÷ºÎÆÄÀÏ ÂüÁ¶ÇϽñ⠹ٶø´Ï´Ù.

* ¸µÅ©´Â ¿©±âÀÔ´Ï´Ù.


 

 ¹øÈ£   Á¦¸ñ ÀÛ¼ºÀÚ ÆÄÀÏ Á¶È¸
   49           [³í¹®] [2016]Comparison of EGFR .. ÆijªÁø 28874
   48           [³í¹®] [2015]IDH Mutation Analys.. ÆijªÁø 65535
   47           [³í¹®] [2015]Low frequency of KR.. ÆijªÁø 29212
   46           [³í¹®] [2015]Simultaneous genoty.. ÆijªÁø 6068
   45           [³í¹®] [2014]Simultaneous diagno.. ÆijªÁø 20975
   44           [³í¹®] [2014]KRAS Mutation Detec.. ÆijªÁø 8125
   43           [³í¹®] [2013]Detection of EGFR m.. ÆijªÁø 1176
   42           [³í¹®] [2013]Detection and compa.. ÆijªÁø 5817
   41           [³í¹®] [2013]Detection of BRAF V.. ÆijªÁø 6098
   40           [³í¹®] [2013]Comparison of Direc.. ÆijªÁø 25287
   39           [³í¹®] [Microarray]Peptide nucle.. ÆijªÁø 14322
   38           [³í¹®] [Clamp]Rapid and Sensitiv.. ÆijªÁø 22243
   37           [³í¹®] [ÆijªÁø Á¦Ç°»ç¿ë ³í¹®] EGFR µ¹¿¬º¯.. ÆijªÁø 3388
   36           [³í¹®] [ÆijªÁø Á¦Ç°»ç¿ë ³í¹®] Development .. ÆijªÁø 14158
   35           [³í¹®] [ÆijªÁø Á¦Ç°»ç¿ë ³í¹®] JHDM3A modul.. ÆijªÁø 1167
¢º           [³í¹®] [PNA Chip vs DNA Chip ÀÓ»ó.. ÆijªÁø 4029
   33           [³í¹®] [ÆijªÁø ³í¹®¹ßÇ¥] PNA-mediated Re.. ÆijªÁø 8823
   32           [³í¹®] [ÆijªÁø Á¦Ç°»ç¿ë ³í¹®] ºñ¼Ò¼¼Æ÷Æó¾Ï¿¡.. ÆijªÁø 14478
   31           [³í¹®] [ÆijªÁø ³í¹® ¹ßÇ¥] PNA-Based Anti.. ÆijªÁø 1172
   30           [³í¹®] [ÆijªÁø ³í¹®¹ßÇ¥]Peptide nucleic .. ÆijªÁø 3894
 

< 1 2 3 >